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ICCB-19 HCl（750621-52-4 free base）

CAS No. 1803605-68-6

ICCB-19 HCl（750621-52-4 free base） ( —— )

Catalog No. M23816 CAS No. 1803605-68-6

ICCB-19 HCl is an inhibitor of TRADD (TNFRSF1A Associated Via Death Domain).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    ICCB-19 HCl（750621-52-4 free base）
  • Note
    Research use only, not for human use.
  • Brief Description
    ICCB-19 HCl is an inhibitor of TRADD (TNFRSF1A Associated Via Death Domain).
  • Description
    ICCB-19 HCl is an inhibitor of TRADD (TNFRSF1A Associated Via Death Domain).?It binds to a pocket on the N-terminal TRAF2-binding domain of TRADD (TRADD-N), which interacts with the C-terminal domain (TRADD-C) and TRAF2 to modulate the ubiquitination of RIPK1 and beclin 1.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    TRADD
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1803605-68-6
  • Formula Weight
    291.8
  • Molecular Formula
    C12H22ClN3OS
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:10 mM
  • SMILES
    C1CCCC(CC1)NC(=O)CSC2=NCCN2.Cl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Xu D , Zhao H , Jin M , et al. Modulating TRADD to restore cellular homeostasis and inhibit apoptosis[J]. Nature, 2020, 587(7832):1-6.
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